ea0022p347 | Diabetes | ECE2010
Paschou Stavroula
, Vartholomatos George
, Kolaitis Nikolaos
, Papadopoulos George
, Tsatsoulis Agathocles
Introduction: T regulatory lymphocytes (Tregs) are defined as CD4+CD25high T lymphocytes and are thought to regulate immune tolerance. The Foxp3 protein level in Tregs is proportional to CD25 protein surface expression and regulatory function, but inversely proportional to IL-7R (CD127) level, the receptor for the growth and survival of T cells. We investigated possible differences in Tregs between newly diagnosed type 1 diabetes (DM1) patients and contro...